Endocrine Abstracts

A 27-year-old lady presented with headache, bilateral papilloedema and long standing thyroid enlargement. Her MRI brain showed a cerebellar lesion. She had surgery and histology was consistent with Lhermitte–Duclos, a benign brain tumour. She also had retinal changes. Her fluroscein angiogram and optical coherence tomography showed multiple retinal harmatomas and pigmented retinal epithelium. She had retrosternal thyroid extension and had total thyroidectomy because of tr...

A 66 year old lady with a previous diagnosis of Retinitis Pigmentosa (RP) was referred to our endocrine clinic with excessive sweating and was also noted to have hypertension, thin skin, extensive bruising and central obesity. Her past medical history included a benign thyroid nodule, gastric erosions, osteoporosis, hyperlipidaemia and depression. On examination, blood pressure was 164/86 mmHg and BMI was 30.7 kg/m2 with central obesity. Biochemical testing revealed...

A 41 year old man was initially referred to lymphoedema clinic. He had leg swelling of 10 years duration but was otherwise fit and well. Examination revealed marked lipohypertrophy affecting his thighs bilaterally. There was no oedema and his distal lower limbs were normal. MRI investigation confirmed focal lipohypertrophy. Biochemical investigation revealed a very low albumin of <10 g/l, a low calcium of 1.96 mmol/l and hyperlipidaemia (cholesterol 9.3 mmol/l, LDL 6.4 mmo...